What inspired you to specialize in regenerative medicine?
Early in my career as an orthopedic surgeon, I became fascinated with the body’s ability to heal itself. Traditional medicine often focuses on symptom management rather than true healing. Regenerative medicine offered an entirely different approach—one that enhances the body’s natural repair mechanisms. I saw firsthand how PRP, stem cell therapy, and other biologics could transform patient outcomes, and I knew this was the future of medicine.
How did you first get involved with EBO2 therapy, and what drew you to this innovative treatment?
I got involved through a colleague in the Dominican Republic who was treating major league baseball players. I’ve always been drawn to therapies that enhance cellular function at the deepest level. EBO2 intrigued me because it optimizes oxygen utilization, removes toxins, and enhances immune function all at once. I started integrating it into my practice after seeing its incredible potential in improving vascular health, reducing inflammation, and enhancing recovery. Over time, I’ve refined its applications and combined it with other regenerative therapies to maximize its benefits.
Can you explain how EBO2 therapy works and how it differs from traditional ozone therapy?
EBO2, or Extracorporeal Blood Oxygenation and Ozonation, is an advanced form of ozone therapy that goes beyond traditional methods. Unlike standard ozone therapy, which typically involves injecting or infusing ozone into the body, EBO2 filters the blood through a dialysis-like system, removing inflammatory proteins, heavy metals, and toxins while super-oxygenating the blood.
A key distinction is that no ozone directly enters the body. Instead, the blood and ozone mix within the dialysis filter, where the ozone is converted into beneficial compounds. This process enhances circulation, reduces inflammation, and supports immune function at a systemic level.
What conditions or diseases respond best to EBO2 therapy?
EBO2 is highly effective for conditions linked to chronic inflammation, poor circulation, and immune dysfunction. This includes cardiovascular disease, autoimmune disorders, Lyme disease, chronic fatigue syndrome, mold toxicity, and even neurodegenerative conditions. Athletes and biohackers also use it to optimize recovery and performance, as well as slow down the aging process.
Are there any particular patient success stories that stand out in your experience with EBO2?
Absolutely. I’ve treated patients with chronic fatigue and autoimmune diseases who, after just a few sessions, experienced significant improvements in energy levels, cognitive function, and overall well-being. One patient with severe Lyme disease had tried nearly everything without success, but after undergoing EBO2 therapy, their symptoms improved dramatically. The ability of this therapy to restore health at a cellular level is truly remarkable.
How does EBO2 therapy compare to other regenerative treatments like stem cells and PRP (Platelet-Rich Plasma)?
EBO2 complements other regenerative therapies rather than replacing them. Stem cell therapy and PRP focus on tissue repair and regeneration, while EBO2 works at the systemic level to optimize cellular function, detoxify the body, and enhance circulation. They create a powerful synergy that accelerates healing and recovery when used together.
What recent advancements in regenerative medicine are you most excited about?
One of the most exciting advancements is plasmapheresis, a cutting-edge therapy that helps reset the body at a cellular level by filtering and rejuvenating the blood. This process removes inflammatory proteins, toxins, and aged plasma components while replenishing the body with healthier plasma. It’s particularly promising in addressing age-related diseases, autoimmune conditions, and chronic inflammation.
Plasmapheresis is gaining traction as a powerful tool for longevity and regenerative medicine because it essentially “cleanses” the bloodstream, allowing cells to function more efficiently. When combined with other regenerative therapies like EBO2, stem cells, and peptides, it creates a comprehensive approach to cellular rejuvenation and optimal health. As research continues, I believe plasmapheresis will play a pivotal role in extending healthspan and improving recovery from chronic conditions.
How do you ensure the safety and efficacy of EBO2 therapy for your patients?
Patient safety is our highest priority. We utilize medical-grade ozone in precise, controlled doses, ensuring all treatments are conducted in a sterile, medically supervised environment under strict protocols. Each patient undergoes thorough screening to determine suitability, and we closely monitor their response to optimize therapy outcomes.
Beyond our own practice, we are leaders in EBO2 education and training, instructing medical professionals across the United States, the Caribbean, Europe, and Turkey. By establishing and upholding the highest standards in EBO2 therapy, we are shaping the future of this advanced treatment worldwide.
Are there any misconceptions about EBO2 therapy that you’d like to address?
One common misconception is the confusion between EBO2 and EBOO—many assume they are the same, but EBO2 is a more advanced and effective version of the therapy. While both involve extracorporeal blood oxygenation and ozonation, EBO2 offers several key advantages.
EBO2 uses a higher dose of ozone, allowing for greater oxygenation and detoxification benefits. It also filters a larger volume of blood, helping to remove more inflammatory proteins, heavy metals, and other toxins. Additionally, EBO2 incorporates a more effective light device, enhancing blood purification and optimizing cellular function far beyond what standard EBOO systems achieve.
Another misconception is that ozone therapy is unsafe. When administered correctly in a controlled setting, EBO2 is a powerful, research-backed therapy that enhances immune function, reduces chronic inflammation, and supports overall longevity.
Where do you see the field of regenerative medicine heading in the next 5-10 years?
Regenerative medicine will continue to shift from isolated treatments to a more holistic, systems-based approach. We’ll see more personalized therapies based on genetic and epigenetic profiling, allowing for highly targeted interventions. Integrating AI and machine learning will also enhance diagnostic accuracy and treatment efficacy.
Are there any upcoming breakthroughs or technologies that you believe will revolutionize this space?
AI and CRISPR are transforming regenerative medicine. AI enables precision diagnostics and personalized treatment plans, optimizing therapies like stem cells and EBO2 for each patient. CRISPR gene-editing technology allows for DNA modifications, correcting mutations, enhancing cellular repair, and potentially reversing aging. Together, these advancements are shifting medicine from reactive treatments to proactive health optimization, paving the way for longer, healthier lives.
What advice would you give to doctors looking to incorporate regenerative therapies like EBO2 into their practice?
Start with a strong foundation in the science behind these therapies. Seek training from experts in the field, stay updated on the latest research, and integrate regenerative medicine in a way that complements existing treatments. Most importantly, focus on patient education—helping them understand how these therapies work will lead to better compliance and outcomes.
What challenges have you faced in promoting regenerative medicine, and how have you overcome them?
One of the biggest challenges has been overcoming skepticism. Regenerative medicine often faces resistance because it challenges traditional medical paradigms. I’ve tackled this by focusing on education—lecturing globally, publishing research, and sharing real-world success stories. As more clinical evidence emerges, the acceptance of these therapies continues to grow.
How do you balance scientific rigor with innovative, cutting-edge treatments?
The key is to remain open to new ideas while maintaining a strong commitment to evidence-based medicine. I always evaluate new treatments through the lens of science, clinical experience, and patient outcomes. Innovation is essential, but it must be backed by data and a clear understanding of the underlying mechanisms.
About Dr. Joseph Purita:
Dr. Joseph Purita is a board-certified orthopedic surgeon and a global regenerative medicine leader specializing in cellular and anti-aging therapies. With over 20 years of experience, he has pioneered advancements in Ozone Therapy and EBO2 (Extracorporeal Blood Oxygenation & Ozonation), lecturing worldwide on cutting-edge treatments.
As the inaugural president of the American Academy and Board of Regenerative Medicine, Dr. Purita has played a key role in shaping the field. He currently serves as the medical director of PUR-FORM and sits on multiple scientific boards. Recently appointed as a Professor of Regenerative Medicine at the University of Max Planck in Brazil, he continues to drive innovation in the field.
About Michele Hughes
Michele Hughes is the visionary founder of Ageless and Timeless and the dynamic host of the Ageless and Timeless podcast. As a monthly contributor to Top Doctor Magazine, she offers powerful insights on wellness, longevity, and living fully at every stage of life. With a deep passion for health, vitality, and a role model for timeless elegance, Michele empowers audiences to embrace their highest potential and live with purpose and grace. Michele’s podcast, Ageless and Timeless, was one of 20 Inaugural Podcasts selected for the Muscle and Fitness Plus platform that began in 2023.
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